Association of perioperative allogeneic blood transfusion with postoperative survival of patients with gastric cancer after curative gastrectomy
  
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DOI:10.46701/APJBG.20170217030
KeyWord:gastric cancer, perioperative allogeneic blood transfusion, survival rates
        
AuthorInstitution
Suliang Li Department of Blood Transfusion, the First Affiliated Hospital of Xi'an Medical University, Xi'an, Shaanxi 710077, China.
Yang Ji Department of Radiology, the First Affiliated Hospital of Xi'an Medical University, Xi'an, Shaanxi 710077, China.
Yun Ye Department of Blood Transfusion, the First Affiliated Hospital of Xi'an Medical University, Xi'an, Shaanxi 710077, China.
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Abstract:
      To explore the association of perioperative allogeneic blood transfusion (PABT) and postoperative survival rates in patients with gastric cancer (GC). In total, 186 patients with gastric cancer accepted curative gastrectomy were divided into three groups, the PABT <2 U group, the PABT > 2 U group, and the no blood transfusion group. The relationships between PABT and clinical pathological parameters were analyzed and their effects on the postoperative survival of patients with GC were studied. Multivariable COX regression results showed that PABT and tumor size are the important factors influencing the postoperative survival of patients with GC (P<0.05). When comparing with the no blood transfusion group and the PABT < 2 U group, the patient’s risk of death in the PABT > 2 U group rises to 3.282 and 2.130 times (95%CI: 1.731-4.886 and 1.194-3.797) (P<0.05), respectively. This study suggests that PABT is significantly associated with postoperative survival after curative gastrectomy in patients with GC.
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